Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006642)
Formula Reactant Doravirine Product Doravirine Metabolite M18
Reactant Info Product Info
Metabolic Type Oxidation - Oxidationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006637 Doravirine Doravirine M9 Metabolite Oxidation - Oxidationn Doravirine [1]
MR006644 Doravirine Doravirine Metabolite M11 Unclear Doravirine [2]
MR006646 Doravirine Doravirine Metabolite M15 Conjugation - N-acetyl cysteine conjugation Doravirine [2]
MR006643 Doravirine Doravirine Metabolite M19 Unclear Doravirine [2]
MR006640 Doravirine Doravirine Metabolite M5 Unclear Doravirine [2]
MR006645 Doravirine Doravirine Metabolite M8 Oxidation - Oxidationn Doravirine [2]
References
1 DrugBank(Pharmacology-Metabolism): Doravirine
2 Characterisation of the absorption, distribution, metabolism, excretion and mass balance of doravirine, a non-nucleoside reverse transcriptase inhibitor in humans. Xenobiotica. 2019 Apr;49(4):422-432.

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