Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006726)
Formula
SVG example
Reactant Duloxetine hydrochloride Product Dihydrodiol duloxetine
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006722 Duloxetine hydrochloride 4-hydroxy duloxetine Oxidation - Hydrolyzationn Duloxetine hydrochloride [1]
MR006715 Duloxetine hydrochloride 5-hydroxy duloxetine Oxidation - Hydrolyzationn Duloxetine hydrochloride [1]
MR006720 Duloxetine hydrochloride 6-hydroxy duloxetine Oxidation - Hydrolyzationn Duloxetine hydrochloride [1]
MR006725 Duloxetine hydrochloride N-desmethyl duloxetine Unclear Duloxetine hydrochloride [2]
MR006724 Duloxetine hydrochloride Thinel alcohol+Naphthol Unclear Duloxetine hydrochloride [2]
References
1 Duloxetine: clinical pharmacokinetics and drug interactions. Clin Pharmacokinet. 2011 May;50(5):281-94.
2 Metabolism, excretion, and pharmacokinetics of duloxetine in healthy human subjects

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