Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006823)
Formula Reactant Sodium oxybate Product Succinic Semialdehyde
Reactant Info Product Info
Metabolic Enzyme Hydroxyacid-oxoacid transhydrogenase (ADHFE1) DME Info
Metabolic Type Oxidation - Oxidationn
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012768 Gamma hydroxybutyric acid Succinic semialdehyde Unclear - Unclear Gamma hydroxybutyric acid [1]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012769 Succinic semialdehyde Succinate Unclear - Unclear Gamma hydroxybutyric acid [1]
MR006824 Succinic Semialdehyde Succinic Acid Oxidation - Oxidationn Sodium oxybate [2]
References
1 U. S. FDA Label -Gamma hydroxybutyric acid
2 Kinetic characterization of human hydroxyacid-oxoacid transhydrogenase: relevance to D-2-hydroxyglutaric and gamma-hydroxybutyric acidurias. J Inherit Metab Dis. 2005;28(6):921-30.

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