Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006824)
Formula Reactant Succinic Semialdehyde Product Succinic Acid
Reactant Info Product Info
Metabolic Enzyme Succinate-semialdehyde dehydrogenase (ALDH5A1) DME Info
Metabolic Type Oxidation - Oxidationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012768 Gamma hydroxybutyric acid Succinic semialdehyde Unclear - Unclear Gamma hydroxybutyric acid [1]
MR006823 Sodium oxybate Succinic Semialdehyde Oxidation - Oxidationn Sodium oxybate [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012769 Succinic semialdehyde Succinate Unclear - Unclear Gamma hydroxybutyric acid [1]
References
1 U. S. FDA Label -Gamma hydroxybutyric acid
2 Kinetic characterization of human hydroxyacid-oxoacid transhydrogenase: relevance to D-2-hydroxyglutaric and gamma-hydroxybutyric acidurias. J Inherit Metab Dis. 2005;28(6):921-30.

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