Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006876)
Formula
SVG example
O-glucuronidation
Reactant ENB577b Product ENB753
Reactant Info Product Info
Metabolic Type Conjugation - O-glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006875 Entrectinib ENB577b Oxidation - Hydrolyzationn Entrectinib [1]
References
1 LC-MS/MS reveals the formation of iminium and quinone methide reactive intermediates in entrectinib metabolism: In vivo and in vitro metabolic investigation

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