Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006935)
Formula	Oxidationn
	Reactant	Macitentan metabolite M4	Product	Macitentan metabolite M5
	Reactant	Reactant Info	Product	Product Info
Metabolic Type	Oxidation - Oxidationn

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR006934	Macitentan	Macitentan metabolite M4	Oxidation - Oxidationn	Macitentan	[1]

Other MR(s) Related to The Product of This MR

Other MR(s) That Metabolize The Produtc of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR006936	Macitentan metabolite M5	Macitentan metabolite M324	Hydrolysis - Hydrolysis	Macitentan	[1]

References
1	Clinical pharmacokinetics and pharmacodynamics of the endothelin receptor antagonist macitentan

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