Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006945)
Formula Reactant Malathion monocarboxylic acid Product Malathion diacid
Reactant Info Product Info
Metabolic Enzyme Carboxylesterase 1 (CES1) DME Info
Metabolic Type Hydrolysis - Hydrolysis
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006947 Malathion Malathion monocarboxylic acid Hydrolysis - Hydrolysis Malathion [1]
MR006944 Malaoxon Malathion monocarboxylic acid Hydrolysis - Hydrolysis Malathion [1]
References
1 Malathion bioactivation in the human liver: the contribution of different cytochrome p450 isoforms. Drug Metab Dispos. 2005 Mar;33(3):295-302.

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