Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006944)
Formula
SVG example
Hydrolysis
Reactant Malaoxon Product Malathion monocarboxylic acid
Reactant Info Product Info
Metabolic Enzyme Carboxylesterase 1 (CES1) DME Info
Metabolic Type Hydrolysis - Hydrolysis
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006943 Malathion Malaoxon Other reaction - Desulfonization Malathion [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006946 Malaoxon Dimethylthiophosphate Oxidation - Oxidationn Malathion [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006947 Malathion Malathion monocarboxylic acid Hydrolysis - Hydrolysis Malathion [1]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006945 Malathion monocarboxylic acid Malathion diacid Hydrolysis - Hydrolysis Malathion [1]
References
1 Malathion bioactivation in the human liver: the contribution of different cytochrome p450 isoforms. Drug Metab Dispos. 2005 Mar;33(3):295-302.

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