Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007014)
Formula
SVG example
Reactant Glyoxylate Product Oxalate
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007015 Glyoxylate Glycine Unclear Glyoxylate [1]
MR007013 Glyoxylate Glycolate Unclear Glyoxylate [1]
MR012765 Glyoxylate Glycolate Unclear - Unclear Gamma hydroxybutyric acid [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000697 CPC-211 Oxalate Unclear CPC-211 [3]
MR001862 Oxaliplatin Oxalate Unclear Oxaliplatin [4], [5], [6], [7]
References
1 Recombinant production of eight human cytosolic aminotransferases and assessment of their potential involvement in glyoxylate metabolism. Biochem J. 2009 Aug 13;422(2):265-72.
2 U. S. FDA Label -Gamma hydroxybutyric acid
3 Determination of dichloroacetate and its metabolites in human plasma by gas chromatography-mass spectrometry J Chromatogr B Biomed Sci Appl. 1997 Dec 5;703(1-2):75-84. doi: 10.1016/s0378-4347(97)00404-0.
4 Roles of Transient Receptor Potential Ankyrin 1 in Oxaliplatin-Induced Peripheral Neuropathy Biol Pharm Bull. 2017;40(7):947-953. doi: 10.1248/bpb.b17-00243.
5 Analytical Methods for Oxalate Quantification: The Ubiquitous Organic Anion. Molecules. 2023 Apr 4;28(7):3206. doi: 10.3390/molecules28073206.
6 Protein-Based Delivery Systems for Anticancer Metallodrugs: Structure and Biological Activity of the Oxaliplatin/-Lactoglobulin Adduct. Pharmaceuticals (Basel). 2022 Mar 30;15(4):425. doi: 10.3390/ph15040425.
7 Nano-scale imaging of dual stable isotope labeled oxaliplatin in human colon cancer cells reveals the nucleolus as a putative node for therapeutic effect. Nanoscale Adv. 2020 Nov 26;3(1):249-262. doi: 10.1039/d0na00685h.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.