Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007049)
Formula
SVG example
O-methylation
Reactant Hydroxyestrone Product 3-O-methoxyestrone
Reactant Info Product Info
Metabolic Enzyme Catechol O-methyltransferase (COMT) DME Info
Metabolic Type Conjugation - O-methylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007047 Hydroxyestrone 2-hydroxyestrone 2-glucuronide Conjugation - O-glucuronidation Hydroxyestrone [1]
MR007048 Hydroxyestrone 2-Methoxyestrone Conjugation - O-methylation Hydroxyestrone [2]
References
1 Structural and functional studies of UDP-glucuronosyltransferases. Drug Metab Rev. 1999 Nov;31(4):817-99.
2 BioTransformer: a comprehensive computational tool for small molecule metabolism prediction and metabolite identification

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