Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007103)
Formula
SVG example
Reactant Nordexfenfluramine Product 1-(3-CF3 -phenyl)-propan-2-one
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007102 Dexfenfluramine Nordexfenfluramine Oxidation - N-dealkylation Dexfenfluramine [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007108 Nordexfenfluramine N-hydroxynordexfenfluramine Unclear Dexfenfluramine [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007107 1-(3-CF3 -phenyl)-propan-2-one 1-(3-CF3 -phenyl)-propan-1,2-diol Unclear Dexfenfluramine [1]
MR007106 1-(3-CF3 -phenyl)-propan-2-one 1-(3-CF3 -phenyl)-propan-2-ol Unclear Dexfenfluramine [1]
MR007104 1-(3-CF3 -phenyl)-propan-2-one M-trifluoromethyl-benzoic acid Unclear Dexfenfluramine [1]
References
1 Metabolism of dexfenfluramine in human liver microsomes and by recombinant enzymes: role of CYP2D6 and 1A2. Pharmacogenetics. 1998 Oct;8(5):423-32.

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