Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007127)
Formula Reactant O-desmethylencainide Product N,O-didesmethylencainide
Reactant Info Product Info
Metabolic Type Oxidation - Demethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007125 Encainide O-desmethylencainide Oxidation - Demethylation Encainide [1], [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007126 O-desmethylencainide 3-methoxy-O-desmethylencainide Conjugation - Methylationn Encainide [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007129 N-desmethylencainide N,O-didesmethylencainide Oxidation - Demethylation Encainide [1]
References
1 Oxidative metabolism of encainide: polymorphism, pharmacokinetics and clinical considerations
2 Polymorphism of human cytochrome P450 2D6 and its clinical significance: Part I. Clin Pharmacokinet. 2009;48(11):689-723.

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