Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007125)
Formula
SVG example
Demethylation
Reactant Encainide Product O-desmethylencainide
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2D6 (CYP2D6) DME Info
Metabolic Type Oxidation - Demethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007128 Encainide N-desmethylencainide Oxidation - Demethylation Encainide [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007126 O-desmethylencainide 3-methoxy-O-desmethylencainide Conjugation - Methylationn Encainide [1]
MR007127 O-desmethylencainide N,O-didesmethylencainide Oxidation - Demethylation Encainide [1]
References
1 Oxidative metabolism of encainide: polymorphism, pharmacokinetics and clinical considerations

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