Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007169)
Formula
SVG example
N-dealkylation
Reactant Famprofazone Product Methamphetamine
Reactant Info Product Info
Metabolic Type Oxidation - N-dealkylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007177 Famprofazone Amphetamine Oxidation - N-dealkylation Famprofazone [1]
MR007178 Famprofazone p-Hydroxydesmethylfamprofazone Multi-steps Reaction - N-dealkylation; p-hydroxylation Famprofazone [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005724 Benzphetamine MethAmphetamine Unclear Benzphetamine [2]
MR010841 Selegiline Methamphetamine Unclear - Unclear Selegiline [3]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007170 Methamphetamine Amphetamine Oxidation - N-demethylation Famprofazone [1]
MR010842 Methamphetamine Amphetamine Unclear - Unclear Selegiline [3]
MR007175 Methamphetamine Ephedrine Pseudoephedrine Oxidation - eta-hydroxylation Famprofazone [1]
MR007173 Methamphetamine p-Hydroxymethamphetamine Oxidation - p-hydroxylation Famprofazone [1]
References
1 Identification of new urinary metabolites of famprofazone in humans
2 DrugBank(Pharmacology-Metabolism):Benzphetamine
3 Physiologically Based Pharmacokinetic Modeling of Transdermal Selegiline and Its Metabolites for the Evaluation of Disposition Differences between Healthy and Special Populations

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