| General Information of This Metabolic Reaction (MR) (ID:
MR007272) |
| Formula |
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| Reactant |
AS-703026 |
Product |
AS-703026 M445 |
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Reactant Info
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Product Info
|
|
Metabolic Enzyme
|
Cytochrome P450 3A4 (CYP3A4)
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DME Info
|
|
Mephenytoin 4-hydroxylase (CYP2C19)
|
DME Info
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| Other MR(s) Related to The Reactant of This MR |
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Other MR(s) That Metabolize The Reactant of This MR
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| References |
| 1 |
Metabolism of the MEK1/2 inhibitor pimasertib involves a novel conjugation with phosphoethanolamine in patients with solid tumors. Drug Metab Dispos. 2017 Feb;45(2):174-182.
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