Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007535)
Formula
CYP2E1 ...
SVG example
Reactant Benzylamine Product Benzamide
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2E1 (CYP2E1) DME Info
Cytochrome P450 2A1 (Cyp2a1) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007552 Benzylamine Benzaldehyde Unclear Benzylamine [1]
MR007548 Benzylamine Benzylamine M14 Unclear Benzylamine [2]
MR007541 Benzylamine Benzylamine M16 Unclear Benzylamine [2]
MR007544 Benzylamine Benzylamine M17 Unclear Benzylamine [2]
MR007553 Benzylamine Hydrogen peroxide Unclear Benzylamine [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012037 Farglitazar Metabolites M3 Benzamide Hydrolysis - Hydrolysis Farglitazar [3]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007536 Benzamide Benzylamine M15 Unclear Benzylamine [2]
MR012038 Benzamide Benzoic acid Hydrolysis - Hydrolysis Farglitazar [3]
References
1 Chronic benzylamine administration in the drinking water improves glucose tolerance, reduces body weight gain and circulating cholesterol in high-fat diet-fed mice
2 Bioactivation of benzylamine to reactive intermediates in rodents: formation of glutathione, glutamate, and peptide conjugates
3 The Degradation Chemistry of Farglitazar and Elucidation of the Oxidative Degradation Mechanisms

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