Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR012037)
Formula
SVG example
Hydrolysis
Reactant Farglitazar Metabolites M3 Product Benzamide
Reactant Info Product Info
Metabolic Type Hydrolysis - Hydrolysis
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012036 Triamide Farglitazar Metabolites M3 Hydrolysis - Hydrolysis Farglitazar [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012039 Farglitazar Metabolites M3 Benzoic acid Hydrolysis - Hydrolysis Farglitazar [1]
MR012040 Farglitazar Metabolites M3 Diacid Hydrolysis - Hydrolysis Farglitazar [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007535 Benzylamine Benzamide Unclear Benzylamine [2]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007536 Benzamide Benzylamine M15 Unclear Benzylamine [2]
MR012038 Benzamide Benzoic acid Hydrolysis - Hydrolysis Farglitazar [1]
References
1 The Degradation Chemistry of Farglitazar and Elucidation of the Oxidative Degradation Mechanisms
2 Bioactivation of benzylamine to reactive intermediates in rodents: formation of glutathione, glutamate, and peptide conjugates

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