Details of the Metabolic Reaction (MR) | INTEDE

General Information of This Metabolic Reaction (MR) (ID: MR007571)
Formula	UGT
	Reactant	NNAL		Product	NNAL-glucuronide
	Reactant	Reactant Info		Product	Product Info
Metabolic Enzyme	UDP-glucuronyltransferase (UGT)					DME Info

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR007570	BRN-3548355	NNAL	Unclear	BRN-3548355	[1], [2]
MR002959	Nicotine	4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol	Unclear	Nicotine	[3]

References
1	Toxicokinetic and Genotoxicity Study of NNK in Male Sprague Dawley Rats Following Nose-Only Inhalation Exposure, Intraperitoneal Injection, and Oral Gavage
2	Characterization of enzymes participating in carbonyl reduction of 4-methylnitrosamino-1-(3-pyridyl)-1-butanone (NNK) in human placenta. Chem Biol Interact. 2001 Jan 30;130-132(1-3):737-48.
3	DrugBank(Pharmacology-Metabolism)Nicotine

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