Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007661)
Formula	Reactant	R-58735	Product	6-hydroxylation of sabeluzole
Formula	Reactant	Reactant Info	Product	Product Info
Metabolic Enzyme	Cytochrome P450 2D6 (CYP2D6)				DME Info
Metabolic Type	Oxidation - 6-hydroxylation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR007662	R-58735	Unclear	Conjugation - Glucuronidation	R-58735	[1]

References
1	Pharmacokinetics of sabeluzole and dextromethorphan oxidation capacity in patients with severe hepatic dysfunction and healthy volunteers. Br J Clin Pharmacol. 2001 Feb;51(2):164-8.

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