Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008325)
Formula
SVG example
Unclear
Reactant PF-04991532 Product PF-04991532 metabolite M3
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008324 PF-04991532 PF-04991532 metabolite M1 Conjugation - Glucuronidation PF-04991532 [1]
MR008326 PF-04991532 PF-04991532 metabolite M4 Oxidation - Hydroxylation PF-04991532 [1]
MR008327 PF-04991532 PF-04991532 metabolite M5 Oxidation - Hydroxylation PF-04991532 [1]
References
1 Metabolism and excretion of (S)-6-(3-cyclopentyl-2-(4-trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid (PF-04991532), a hepatoselective glucokinase activator, in humans: confirmation of the MIST potential noted in first-in-Human metabolite scouting studies

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