Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008356)
Formula
SVG example
Hydroxylation
Reactant PD-143188 Product PD-147693
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2D6 (CYP2D6) DME Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008360 PD-143188 PD-149394 Oxidation - Hydroxylation PD-143188 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008357 PD-147693 PD-155144 Oxidation - Hydroxylation PD-143188 [1]
MR008364 PD-147693 PD-163637 Conjugation - Sulfation PD-143188 [1]
References
1 Disposition of the antipsychotic agent CI-1007 in rats, monkeys, dogs, and human cytochrome P450 2D6 extensive metabolizers. Species comparison and allometric scaling

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