Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008491)
Formula	CYP3A4 ... Unclear
	Reactant	Remogliflozin	Product	GSK279782
	Reactant	Reactant Info	Product	Product Info
Metabolic Enzyme	Cytochrome P450 3A4 (CYP3A4)				DME Info
	Mephenytoin 4-hydroxylase (CYP2C19)				DME Info
	Cytochrome P450 2C9 (CYP2C9)				DME Info
Metabolic Type	Unclear - Unclear

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR008486	Remogliflozin etabonate	Remogliflozin	Unclear - Unclear	Remogliflozin etabonate	[1]

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR008487	Remogliflozin	GSK1132678	Unclear - Unclear	Remogliflozin etabonate	[1]
MR008495	Remogliflozin	GSK1997714	Unclear - Unclear	Remogliflozin etabonate	[1]
MR008493	Remogliflozin	GSK333081	Unclear - Unclear	Remogliflozin etabonate	[1]

Other MR(s) Related to The Product of This MR

Other MR(s) That Metabolize The Produtc of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR008492	GSK279782	GSK355993	Unclear - Unclear	Remogliflozin etabonate	[1]

References
1	Assessment of the drug interaction risk for remogliflozin etabonate, a sodium-dependent glucose cotransporter-2 inhibitor: evidence from in vitro, human mass balance, and ketoconazole interaction studies

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