Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008696)
Formula Reactant 3,4-Dihydroxyphenylacetone Product 3,4-Dihydroxyphenylacetone glucuronide
Reactant Info Product Info
Metabolic Enzyme UDP-glucuronyltransferase (UGT) DME Info
Metabolic Type Conjugation - Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008695 Methyldopate Hydrochloride 3,4-Dihydroxyphenylacetone Multi-steps Reaction - Deamination; decarboxylation Methyldopate Hydrochloride [1], [2], [3]
References
1 THE METABOLISM OF METHYLDOPA IN HYPERTENSIVE HUMAN SUBJECTS
2 Clinical pharmacokinetics of methyldopa
3 Reaction of dopa decarboxylase with alpha-methyldopa leads to an oxidative deamination producing 3,4-dihydroxyphenylacetone, an active site directed affinity label

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