Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008710)
Formula
SVG example
Unclear
Reactant Imidaprilat Product Imidapril Metabolite M4
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008709 Imidapril Imidaprilat Unclear - Unclear Imidapril [1]
MR006471 TA-6366 Imidaprilat Hydrolysis - Hydrolysis TA-6366 [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008711 Imidaprilat Imidapril Metabolite M2 Unclear - Unclear Imidapril [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008713 Imidapril Metabolite M3 Imidapril Metabolite M4 Unclear - Unclear Imidapril [3]
References
1 Radioimmunoassay for imidapril, a new angiotensin-converting enzyme inhibitor, and imidaprilat, its active metabolite, in human plasma and urine
2 Inhibition of human liver carboxylesterase (hCE1) by organophosphate ester flame retardants and plasticizers: implications for pharmacotherapy. Toxicol Sci. 2019 Jul 3. pii: kfz149.
3 Metabolic fate of the new angiotensin-converting enzyme inhibitor imidapril in animals. 5th communication: isolation and identification of metabolites of imidapril in rats, dogs, and monkeys

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