Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008825)
Formula
CYP2C9 ...
SVG example
Hydroxylation
Reactant Nalbuphine Product 3'-hydroxynalbuphine
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2C9 (CYP2C9) DME Info
Mephenytoin 4-hydroxylase (CYP2C19) DME Info
Cytochrome P450 2D6 (CYP2D6) DME Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008826 Nalbuphine 4'-hydroxynalbuphine Oxidation - Hydroxylation Nalbuphine [1]
MR008827 Nalbuphine Nalbuphine-3-beta-D-glucuronide Conjugation - Glucuronidation Nalbuphine [1]
MR008828 Nalbuphine Nalbuphine-6-beta-D-glucuronide Conjugation - Glucuronidation Nalbuphine [1]
References
1 A dual system platform for drug metabolism: Nalbuphine as a model compound

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