Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008942)
Formula	CYP3A4 Demethylation
	Reactant	Betrixaban	Product	O-desmethylbetrixaban
	Reactant	Reactant Info	Product	Product Info
Metabolic Enzyme	Cytochrome P450 3A4 (CYP3A4)				DME Info
Metabolic Type	Oxidation - Demethylation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR008943	Betrixaban	N-desmethylbetrixaban	Oxidation - N-demethylation	Betrixaban	[1]
MR008944	Betrixaban	PRT062802	Hydrolysis - Hydrolysis	Betrixaban	[1]
MR008938	Betrixaban	PRT062803	Hydrolysis - Hydrolysis	Betrixaban	[1]

References
1	DrugBank(Pharmacology-Metabolism):Betrixaban

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