Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008990)
Formula Reactant Almogran metabolite A2 Product Almogran metabolite P15
Reactant Info Product Info
Metabolic Enzyme Aldehyde dehydrogenase (ALDH) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008989 2-OH-almotriptan Almogran metabolite A2 Unclear - Unclear Almogran [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008991 Almogran Almogran metabolite P15 Oxidation - Oxidation Almogran [2]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008992 Almogran metabolite P15 Almogran metabolite P13 Oxidation - N-demethylation Almogran [2]
MR008994 Almogran metabolite P15 Almogran metabolite P23 Oxidation - N-oxidation Almogran [2]
MR008993 Almogran metabolite P15 Almogran metabolite P6 Oxidation - N-dealkylation Almogran [2]
References
1 Almotriptan, a new anti-migraine agent: a review. CNS Drug Rev. 2002 Fall;8(3):217-34.
2 Disposition and metabolism of almotriptan in rats, dogs and monkeys Xenobiotica. 2006 Sep;36(9):807-23. doi: 10.1080/00498250600802508.

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