Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009271)
Formula Reactant LAROPIPRANT Product LAROPIPRANT Metabolite M5
Reactant Info Product Info
Metabolic Type Oxidation - N-dealkylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009267 LAROPIPRANT LAROPIPRANT Metabolite M1 Oxidation - Monohydroxylation LAROPIPRANT [1]
MR009265 LAROPIPRANT LAROPIPRANT Metabolite M2 Conjugation - Acyl glucuronide conjugation LAROPIPRANT [1]
MR009263 LAROPIPRANT LAROPIPRANT Metabolite M3 Unclear - Unclear LAROPIPRANT [1]
MR009269 LAROPIPRANT LAROPIPRANT Metabolite M4 Oxidation - Monohydroxylation LAROPIPRANT [1]
MR009272 LAROPIPRANT LAROPIPRANT Metabolite M7 Oxidation - Oxidization LAROPIPRANT [1]
References
1 Metabolism of MK-0524, a prostaglandin D2 receptor 1 antagonist, in microsomes and hepatocytes from preclinical species and humans

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