Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009384)
Formula
SVG example
Retro aldol condensation
Reactant Nitecapone Product DP1
Reactant Info Product Info
Metabolic Type Other reaction - Retro aldol condensation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009375 Nitecapone Nitecapone Metabolite M1 Reduction - Reduction Nitecapone [1]
MR009377 Nitecapone Nitecapone Metabolite M10 Unclear - Unclear Nitecapone [1]
MR009372 Nitecapone Nitecapone Metabolite M3 Reduction - Reduction Nitecapone [1]
MR009386 Nitecapone Nitecapone Metabolite M6 Conjugation - O-Methylation Nitecapone [1]
MR009388 Nitecapone Nitecapone Metabolite M8 Oxidation - Deacetylation Nitecapone [1]
MR009380 Nitecapone Nitecapone Metabolite M9 Unclear - Unclear Nitecapone [1]
MR009389 Nitecapone Nitecapone Metabolite MI Conjugation - Sulfitation Nitecapone [2]
MR009390 Nitecapone Nitecapone Metabolite MXII Unclear - Unclear Nitecapone [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006874 Entacapone cis-isomer 3,4-Dihydroxy-5-nitrobenzaldehyde Oxidation - Hydrolyzationn Entacapone [3]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009385 DP1 DP2 Oxidation - Oxidation Nitecapone [1]
References
1 The equine metabolism of the catechol-O-methyltransferase enzyme inhibitor nitecapone
2 Identification of major metabolites of the catechol-O-methyltransferase inhibitor nitecapone in the rat and dog
3 European?Medicines?Agency?(EMA),?Committee?for?Medicinal?Products?for?Human?Use?(CHMP

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