Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009408)
Formula
DCK
SVG example
Unclear
Reactant PSI-6130 Product PSI-6130-MP
Reactant Info Product Info
Metabolic Enzyme Deoxycytidine kinase (DCK) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009407 R7128 PSI-6130 Unclear - Unclear R7128 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009412 PSI-6130-MP PSI-6130-DP Unclear - Unclear R7128 [2]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009412 PSI-6130-MP PSI-6130-DP Unclear - Unclear R7128 [2]
MR009409 PSI-6130-MP RO2433-MP Unclear - Unclear R7128 [2]
MR009413 PSI-6130-DP PSI-6130-TP Unclear - Unclear R7128 [2]
References
1 Selected replicon variants with low-level in vitro resistance to the hepatitis C virus NS5B polymerase inhibitor PSI-6130 lack cross-resistance with R1479
2 Characterization of the metabolic activation of hepatitis C virus nucleoside inhibitor beta-D-2'-Deoxy-2'-fluoro-2'-C-methylcytidine (PSI-6130) and identification of a novel active 5'-triphosphate species

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.