Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009409)
Formula Reactant PSI-6130-MP Product RO2433-MP
Reactant Info Product Info
Metabolic Enzyme Deoxycytidylate deaminase (DCTD) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009408 PSI-6130 PSI-6130-MP Unclear - Unclear R7128 [1]
MR009412 PSI-6130-MP PSI-6130-DP Unclear - Unclear R7128 [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009412 PSI-6130-MP PSI-6130-DP Unclear - Unclear R7128 [1]
MR009413 PSI-6130-DP PSI-6130-TP Unclear - Unclear R7128 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009414 RO2433-MP RO2433 Unclear - Unclear R7128 [1]
MR009410 RO2433-MP RO2433-DP Unclear - Unclear R7128 [1]
References
1 Characterization of the metabolic activation of hepatitis C virus nucleoside inhibitor beta-D-2'-Deoxy-2'-fluoro-2'-C-methylcytidine (PSI-6130) and identification of a novel active 5'-triphosphate species

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