Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009443)
Formula
SVG example
Unclear
Reactant BMS-204352 Product BMS-204352 Metabolite M2
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009445 BMS-204352 BMS-204352 Metabolite M1 Conjugation - Glucuronidation BMS-204352 [1]
MR009457 BMS-204352 GW-501516 Metabolite M4 Unclear - Unclear GW-501516 [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009444 BMS-204352 Metabolite M2 BMS-204352 Metabolite M3 Hydrolysis - Hydrolysis BMS-204352 [3]
References
1 Amide N-glucuronidation of MaxiPost catalyzed by UDP-glucuronosyltransferase 2B7 in humans
2 Metabolic study of GW1516 in equine urine using liquid chromatography/electrospray ionization Q-Exactive high-resolution mass spectrometry for doping control
3 Metabolism, pharmacokinetics, and protein covalent binding of radiolabeled MaxiPost (BMS-204352) in humans

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