Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009630)
Formula
SVG example
Glucuronidation
Reactant 5,6-epoxy-RA Product Rac-5,6-Epoxy-retinoyl-beta-D-glucuronide
Reactant Info Product Info
Metabolic Type Conjugation - Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006382 NSC-122758 5,6-Epoxyretinoic acid Unclear NSC-122758 [1]
MR009629 Tretinoin 5,6-epoxy-RA Oxidation - Ring epoxidation Tretinoin [2], [2], [1]
References
1 Identification of human cytochrome P450s involved in the formation of all-trans-retinoic acid principal metabolites. Mol Pharmacol. 2000 Dec;58(6):1341-8.
2 Retinoic acid metabolism and mechanism of action: a review

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