Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009646)
Formula
SVG example
Hydroxylation
Reactant Zaltoprofen Product 10-OH-zaltoprofen (M3)
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2C9 (CYP2C9) DME Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009648 Zaltoprofen Zaltoprofen acyl glucuronide Conjugation - Glucuronidation Zaltoprofen [1]
MR009644 Zaltoprofen Zaltoprofen S-oxide (M2) Oxidation - Oxidation Zaltoprofen [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009647 10-OH-zaltoprofen (M3) 10-OH-zaltoprofen S-oxide (M5) Oxidation - Oxidation Zaltoprofen [1]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

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