General Information of This Metabolic Reaction (MR) (ID: MR009898)
Formula
SVG example
Unclear
Reactant 6-mercaptopurine Product 6-thioinosine-monophosphate
Reactant Info Product Info
Metabolic Enzyme Hypoxanthine phosphoribosyltransferase (HPRT1) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009897 Azathioprine 6-mercaptopurine Unclear - Non-enzymaticreduction Azathioprine [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009902 6-mercaptopurine 6-methylmercaptopurine Unclear - Unclear Azathioprine [1]
MR009903 6-mercaptopurine 6-thioxanthine Unclear - Unclear Azathioprine [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009899 6-thioinosine-monophosphate 6-thioxanthosine-monophosphate Unclear - Unclear Azathioprine [1]
MR009901 6-thioinosine-monophosphate Methyl-6-thioinosine-monophosphate Unclear - Unclear Azathioprine [1]
References
1 Gut Microbiota Metabolism of Azathioprine: A New Hallmark for Personalized Drug-Targeted Therapy of Chronic Inflammatory Bowel Disease

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