Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009950)
Formula
SVG example
HYDROXYLATION
Reactant Elvitegravir Product Elvitegravir Metabolite M1
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Oxidation - HYDROXYLATION
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009951 Elvitegravir Elvitegravir Metabolite M4 Conjugation - Glucuronidation Elvitegravir [1]
References
1 In vitro resistance selections using elvitegravir, raltegravir, and two metabolites of elvitegravir M1 and M4

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