Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009981)
Formula
SVG example
Unclear
Reactant Mercaptopurine Product 6-methylmercaptopurine
Reactant Info Product Info
Metabolic Enzyme Thiopurine methyltransferase (TPMT) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009972 Mercaptopurine 6-thioinosine monophosphate Unclear - Unclear Mercaptopurine [1], [2]
MR009982 Mercaptopurine 6-thiouric acid Unclear - Unclear Mercaptopurine [1], [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009902 6-mercaptopurine 6-methylmercaptopurine Unclear - Unclear Azathioprine [3]
References
1 Azathioprine and 6-mercaptopurine pharmacogenetics and metabolite monitoring in inflammatory bowel disease
2 6-Mercaptopurine metabolism in Crohn's disease: correlation with efficacy and toxicity
3 Gut Microbiota Metabolism of Azathioprine: A New Hallmark for Personalized Drug-Targeted Therapy of Chronic Inflammatory Bowel Disease

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