Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR010028)
Formula
SVG example
Unclear
Reactant Rabeprazole sodium Product Rabeprazole?sulfone
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010026 Rabeprazole sodium Desmethyl?rabeprazole?thioether Unclear - Unclear Rabeprazole sodium [1]
MR010027 Rabeprazole sodium Desmethylrabeprazole Unclear - Unclear Rabeprazole sodium [2]
MR010025 Rabeprazole sodium Rabeprazole?thioether Unclear - Unclear Rabeprazole sodium [3]
References
1 Simultaneous determination of rabeprazole and its two active metabolites in human urine by liquid chromatography with tandem mass spectrometry and its application in a urinary excretion study
2 Determination of rabeprazole enantiomers and their metabolites by high-performance liquid chromatography with solid-phase extraction
3 Determination of rabeprazole and its active metabolite, rabeprazole thioether in human plasma by column-switching high-performance liquid chromatography and its application to pharmacokinetic study

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