Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR010182)
Formula
CYP3A4 ...
SVG example
Unclear
Reactant Mavacamten Product MYK-1078
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 3A5 (CYP3A5) DME Info
Mephenytoin 4-hydroxylase (CYP2C19) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010179 Mavacamten Mavacamten Metabolite M10 Unclear - Unclear Mavacamten [1]
MR010180 Mavacamten Mavacamten Metabolite M11 Unclear - Unclear Mavacamten [1]
MR010181 Mavacamten Mavacamten Metabolite M13 Unclear - Unclear Mavacamten [1]
MR010176 Mavacamten MYK-2210 Unclear - Unclear Mavacamten [1]
MR010178 Mavacamten MYK-2241 Unclear - Unclear Mavacamten [1]
References
1 In vitro and in vivo pharmacokinetic characterization of mavacamten, a first-in-class small molecule allosteric modulator of beta cardiac myosin

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