Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR010377)
Formula
SVG example
Di-desmethylation
Reactant MmBPU Product AminoBPU
Reactant Info Product Info
Metabolic Type Oxidation - Di-desmethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010376 Benzoylphenylurea MmBPU Oxidation - Desmethylation Benzoylphenylurea [1], [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010380 MmBPU G280 Unclear - Unclear Benzoylphenylurea [1], [2]
MR010379 MmBPU G308 Unclear - Unclear Benzoylphenylurea [1], [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010378 AminoBPU G322 Unclear - Unclear Benzoylphenylurea [1], [2]
References
1 In vitro and in vivo clinical pharmacology of dimethyl benzoylphenylurea, a novel oral tubulin-interactive agent
2 Phase I study of continuous weekly dosing of dimethylamino benzoylphenylurea (BPU) in patients with solid tumours

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