Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR010407)
Formula Reactant ABT-450 Product ABT-450 Metabolite M24
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Multi-steps Reaction - Oxidation& conjugation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010408 ABT-450 ABT-450 Metabolite M13 Hydrolysis - Hydrolysis ABT-450 [1]
MR010410 ABT-450 ABT-450 Metabolite M14 Multi-steps Reaction - Oxidation; hydrolysis ABT-450 [1]
MR010409 ABT-450 ABT-450 Metabolite M16 Multi-steps Reaction - Oxidation; hydrolysis ABT-450 [1]
MR010406 ABT-450 ABT-450 Metabolite M2 Oxidation - Oxidation ABT-450 [1]
MR010411 ABT-450 ABT-450 Metabolite M22 Multi-steps Reaction - Oxidation; hydrolysis ABT-450 [1]
MR010404 ABT-450 ABT-450 Metabolite M25 Hydrolysis - Hydrolysis ABT-450 [1]
MR010402 ABT-450 ABT-450 Metabolite M29 Hydrolysis - Hydrolysis ABT-450 [1]
MR010400 ABT-450 ABT-450 Metabolite M6 Oxidation - Oxidation ABT-450 [1]
References
1 Metabolism and Disposition of the Hepatitis C Protease Inhibitor Paritaprevir in Humans

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