Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR010443)
Formula Reactant Paritaprevir Product Paritaprevir Metabolite M24
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Multi-steps Reaction - Oxidation& conjugation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010444 Paritaprevir Paritaprevir Metabolite M13 Hydrolysis - Hydrolysis Paritaprevir [1]
MR010446 Paritaprevir Paritaprevir Metabolite M14 Multi-steps Reaction - Oxidation; hydrolysis Paritaprevir [1]
MR010445 Paritaprevir Paritaprevir Metabolite M16 Multi-steps Reaction - Oxidation; hydrolysis Paritaprevir [1]
MR010442 Paritaprevir Paritaprevir Metabolite M2 Oxidation - Oxidation Paritaprevir [1]
MR010447 Paritaprevir Paritaprevir Metabolite M22 Multi-steps Reaction - Oxidation; hydrolysis Paritaprevir [1]
MR010440 Paritaprevir Paritaprevir Metabolite M25 Hydrolysis - Hydrolysis Paritaprevir [1]
MR010438 Paritaprevir Paritaprevir Metabolite M29 Hydrolysis - Hydrolysis Paritaprevir [1]
MR010436 Paritaprevir Paritaprevir Metabolite M6 Oxidation - Oxidation Paritaprevir [1]
References
1 Metabolism and Disposition of the Hepatitis C Protease Inhibitor Paritaprevir in Humans

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