Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR010771)
Formula
CYP3A4 ...
SVG example
Dealkylation
Reactant Nalmefene Product Nornalmefene
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 3A5 (CYP3A5) DME Info
Metabolic Type Oxidation - Dealkylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010774 Nalmefene Nalmefene 3-O-glucuronide Conjugation - O-glucuronidation Nalmefene [1]
MR010775 Nalmefene Nalmefene 3-O-sulfate Conjugation - Sulfation Nalmefene [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010773 Nornalmefene Nornalmefene 3-O-glucuronide Conjugation - O-glucuronidation Nalmefene [2]
MR010772 Nornalmefene Nornalmefene 3-O-sulfate Conjugation - Sulfation Nalmefene [2]
References
1 Isolation of a novel morphinan 3-O-diglucuronide metabolite from dog urine
2 LABEL:Nalmefene

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.