Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR010802)
Formula
SVG example
Unclear
Reactant Triamcinolone Product 6-beta-hydroxytriamcinolone Acetonide
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010804 Triamcinolone 21-carboxy-6-beta-6-beta-hydroxytriamcinolone Acetonide Unclear - Unclear Triamcinolone [1]
MR010803 Triamcinolone 21-carboxytriamcinolone acetonide Unclear - Unclear Triamcinolone [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002449 Triamcinolone diacetate 6-beta-hydroxy-triamcinolone Oxidation - 6-Beta-Hydroxylation Triamcinolone diacetate [2], [3], [4]
References
1 PubChem:Triamcinolone
2 A mass balance study to evaluate the biotransformation and excretion of [14C]-triamcinolone acetonide following oral administration J Clin Pharmacol. 2000 Jul;40(7):770-80. doi: 10.1177/00912700022009413.
3 Metabolic fate of a synthetic corticosteroid (triamcinolone) in the dog J Biol Chem. 1961 Apr;236:1038-42.
4 Metabolic pathways of inhaled glucocorticoids by the CYP3A enzymes. Drug Metab Dispos. 2013 Feb;41(2):379-89.

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