Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR010837)
Formula
SVG example
Unclear
Reactant Efinaconazole Product Efinaconazole H3
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013247 UK-51,060 UK-215,364 Unclear Voriconazole [1], [2]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013248 UK-215,364 Voriconazole O-glucuronide derivative (1) Conjugation - Glucuronidation Voriconazole [1], [2]
MR013249 UK-215,364 Voriconazole O-glucuronide derivative (2) Conjugation - Glucuronidation Voriconazole [1], [2]
References
1 The disposition of voriconazole in mouse, rat, rabbit, guinea pig, dog, and human
2 Roles of CYP3A4 and CYP2C19 in methyl hydroxylated and N-oxidized metabolite formation from voriconazole, a new anti-fungal agent, in human liver microsomes. Biochem Pharmacol. 2007 Jun 15;73(12):2020-6.

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