Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR010977)
Formula
UGT
SVG example
O-glucuronidation
Reactant Exjade Product Exjade Metabolite M3
Reactant Info Product Info
Metabolic Enzyme UDP-glucuronyltransferase (UGT) DME Info
Metabolic Type Conjugation - O-glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010978 Exjade Exjade Metabolite M1 Oxidation - Hydroxylation Exjade [1]
MR010979 Exjade Exjade Metabolite M2 Oxidation - Hydroxylation Exjade [1]
MR010980 Exjade Exjade Metabolite M4 Oxidation - Hydroxylation Exjade [1]
MR010981 Exjade Exjade Metabolite M6 Conjugation - O-glucuronidation Exjade [1]
References
1 Pharmacokinetics, distribution, metabolism, and excretion of deferasirox and its iron complex in rats Drug Metab Dispos. 2008 Dec;36(12):2523-38. doi: 10.1124/dmd.108.022962.

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