General Information of This Metabolic Reaction (MR) (ID: MR011207)
Formula
SVG example
N-demethylation
Reactant Hydrocodone M272 Product Hydrocodone M274
Reactant Info Product Info
Metabolic Type Oxidation - N-demethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011210 Hydrocodone Hydrocodone M272 Multi-steps Reaction - N-demethylation; O-demethylation Hydrocodone [1]
MR011206 Norhydrocodone Hydrocodone M272 Multi-steps Reaction - N-demethylation; O-demethylation Hydrocodone [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011216 Hydrocodone M272 Hydrocodone M488 Conjugation - Glucuronidation Hydrocodone [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011203 Hydromorphol Hydrocodone M274 Oxidation - N-demethylation Hydrocodone [1]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR014002 Hydrocodone M274 Hydrocodone M450 Conjugation - Glucuronidation Hydrocodone [1]
MR011204 Hydrocodone M274 Hydrocodone M450 Conjugation - Glucuronidation Hydrocodone [1]
References
1 Update on hydrocodone metabolites in rats and dogs aided with a semi-automatic software for metabolite identification Mass-MetaSite

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