Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR011210)
Formula	N-demethylation; O-demethylation
	Reactant	Hydrocodone	Product	Hydrocodone M272
	Reactant	Reactant Info	Product	Product Info
Metabolic Type	Multi-steps Reaction - N-demethylation; O-demethylation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR011212	Hydrocodone	Hydrocodol	Reduction - Ketone reduction	Hydrocodone	[1]
MR011218	Hydrocodone	Hydrocodone N-oxide-1	Oxidation - N-oxidation	Hydrocodone	[1]
MR011201	Hydrocodone	Hydromorphone	Oxidation - O-demethylation	Hydrocodone	[1]
MR011205	Hydrocodone	Norhydrocodone	Oxidation - N-demethylation	Hydrocodone	[1]

Other MR(s) Related to The Product of This MR

Other MR(s) That Produce The Product of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR011206	Norhydrocodone	Hydrocodone M272	Multi-steps Reaction - N-demethylation; O-demethylation	Hydrocodone	[1]

Other MR(s) That Metabolize The Produtc of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR014001	Hydrocodone M272	Hydrocodone M274	Oxidation - N-demethylation	Hydrocodone	[1]
MR011216	Hydrocodone M272	Hydrocodone M488	Conjugation - Glucuronidation	Hydrocodone	[1]
MR011207	Hydrocodone M272	Hydrocodone M274	Oxidation - N-demethylation	Hydrocodone	[1]

References
1	Update on hydrocodone metabolites in rats and dogs aided with a semi-automatic software for metabolite identification Mass-MetaSite

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