General Information of This Metabolic Reaction (MR) (ID: MR011356)
Formula
CYP2C8 ...
SVG example
Unclear
Reactant AMG 853 Product AMG 853 Metabolite M3
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2C8 (CYP2C8) DME Info
Cytochrome P450 2J2 (CYP2J2) DME Info
Cytochrome P450 3A (CYP3A) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011354 AMG 853 AMG 853 Metabolite M1 Conjugation - Glucuronidation AMG 853 [1]
MR011355 AMG 853 AMG 853 Metabolite M2 Unclear - Unclear AMG 853 [1]
References
1 Predicting the drug interaction potential of AMG 853, a dual antagonist of the D-prostanoid and chemoattractant receptor-homologous molecule expressed on T helper 2 cells receptors

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