Details of the Metabolic Reaction (MR) | INTEDE

General Information of This Metabolic Reaction (MR) (ID: MR011356)
Formula	CYP2C8 ... Unclear
	Reactant	AMG 853		Product	AMG 853 Metabolite M3
	Reactant	Reactant Info		Product	Product Info
Metabolic Enzyme	Cytochrome P450 2C8 (CYP2C8)					DME Info
	Cytochrome P450 2J2 (CYP2J2)					DME Info
	Cytochrome P450 3A (CYP3A)					DME Info
Metabolic Type	Unclear - Unclear

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR011354	AMG 853	AMG 853 Metabolite M1	Conjugation - Glucuronidation	AMG 853	[1]
MR011355	AMG 853	AMG 853 Metabolite M2	Unclear - Unclear	AMG 853	[1]

References
1	Predicting the drug interaction potential of AMG 853, a dual antagonist of the D-prostanoid and chemoattractant receptor-homologous molecule expressed on T helper 2 cells receptors

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