General Information of This Metabolic Reaction (MR) (ID: MR011579)
Formula
CYP3A4 ...
SVG example
Unclear
Reactant SUVN-G3031 Product SUVN-G3031 Metabolite MA
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Monoamine oxidase type A (MAO-A) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011580 SUVN-G3031 SUVN-G3031 Metabolite MB Unclear - Unclear SUVN-G3031 [1]
MR011581 SUVN-G3031 SUVN-G3031 Metabolite MC Unclear - Unclear SUVN-G3031 [1]
MR011582 SUVN-G3031 SUVN-G3034 Metabolite MD Oxidation - Dealkylation SUVN-G3031 [1]
References
1 Absorption, distribution, metabolism, excretion (ADME), drug-drug interaction potential and prediction of human pharmacokinetics of SUVN-G3031, a novel histamine 3 receptor (H(3)R) inverse agonist in clinical development for the treatment of narcolepsy

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